Zopinap vs Zopfresh – Which Is Better for Insomnia?
The Silent Torture of Sleepless Nights
It starts the same way every night. You lay your head on the pillow, close your eyes, and hope tonight will be different. But 20 minutes later, your mind is racing. You shift positions. You count sheep. You scroll your phone. By the time you glance at the clock again- it’s 3 a.m.
Tomorrow will be brutal. You’ll drag yourself to work, fueled by coffee, pretending you’re okay when deep down you feel like you’re unraveling.
If this sounds familiar, you’re not alone. Insomnia affects over 35% of adults worldwide. And if you’ve been living with it, you already know: it’s not just about sleep- it’s about your entire life.
- Your job performance suffers.
- Your relationships are strained.
- Your health declines with every sleepless night.
Most people try home remedies first: chamomile tea, yoga, no screens before bed. But when these fail, you’re left asking: “What actually works?”
That’s where prescription sleep aids like Zopinap and Zopfresh come in. But here’s the catch- they both contain the same ingredient, yet patients often wonder: “Which one is better for me?”

The Problem: Confusion That Costs You Sleep
Zopinap and Zopfresh are both Zopiclone-based sleep medicines. On paper, they look identical. But when you dig deeper, you’ll see differences in strength, dosage options, and suitability for different types of insomnia.
This confusion leaves patients stuck:
- Afraid of picking the wrong one
- Unsure about safety
- Worried about wasting money
And the cost of staying confused? Another night lost to insomnia. Another day of fatigue, irritability, and brain fog.

A Clear Comparison That Ends the Guesswork
Here’s the truth: both Zopinap and Zopfresh are effective- but they’re designed for slightly different needs.
What Is Zopinap?
Zopinap is a prescription hypnotic that helps you fall asleep faster and stay asleep longer.
- Strengths: 10 mg, 20 mg
- Best for: Severe or resistant insomnia cases
- How it works: Enhances the calming neurotransmitter GABA, slowing brain activity so your body can rest
Why it matters: If you’ve tried lower-dose sleep aids with no success, Zopinap’s 20 mg option can provide stronger, guaranteed relief.

What Is Zopfresh?
Zopfresh is another brand of Zopiclone, available in smaller strengths.
- Strengths: 7.5 mg, 10 mg
- Best for: First-time users or moderate insomnia
- How it works: Same mechanism as Zopinap, but in gentler doses
Why it matters: Perfect if you’re new to prescription sleep aids and want a safer starting point with less risk of morning grogginess.

Zopinap vs Zopfresh: The Breakdown
Feature | Zopinap | Zopfresh |
Active Ingredient | Zopiclone | Zopiclone |
Strengths | 10 mg, 20 mg | 7.5 mg, 10 mg |
Best For | Severe insomnia, resistant cases | Mild–moderate insomnia, beginners |
Onset of Action | 20–30 minutes | 20–30 minutes |
Duration | 6–8 hours | 6–8 hours |
Risk of Dependence | Slightly higher (20 mg dose) | Lower (7.5–10 mg) |
Key Insight: Both work, but Zopinap provides stronger relief for stubborn insomnia, while Zopfresh offers a gentler introduction to sleep medicine.

Why People Trust These Medicines
- Doctors prescribe Zopiclone-based medicines worldwide as a clinically proven, first-line solution for short-term insomnia.
- Thousands of patients report falling asleep within 30 minutes and staying asleep for 6-8 hours after taking Zopinap or Zopfresh.
- Untreated insomnia increases risks of anxiety, depression, obesity, diabetes, and even heart disease. Every night lost isn’t just sleep- it’s your health slipping away.

Dosage & Administration Guidelines
Whether you’re taking Zopinap or Zopfresh, follow these rules:
- Take once daily, right before bedtime.
- Swallow whole with water- never crush or chew.
- Ensure 7–8 hours of sleep opportunity.
- Avoid alcohol or other sedatives.
Use short-term only (2–4 weeks).

Side Effects & Safety
Like any sleep medicine, side effects may occur:
- Bitter or metallic taste
- Next-day drowsiness
- Dizziness or headache
- Rare: memory issues or sleepwalking
Seek medical help immediately if you experience confusion, hallucinations, or breathing problems.

Handling Your Concerns
“Aren’t these addictive?”
Not if used correctly. Dependence usually occurs only with misuse or long-term daily use beyond 4 weeks.
“What if it doesn’t work for me?”
That’s why having both lower-dose Zopfresh and higher-dose Zopinap available is important. You and your doctor can adjust until you find the dosage that works.

Cost & Availability
- Zopinap: Slightly higher due to 20 mg strength.
- Zopfresh: More affordable for entry-level use.
On Medicine Mart, you can compare prices across multiple suppliers, ensuring you never overpay.
- Zopinap 10 mg
- Zopinap 20 mg
- Zopfresh 7.5 mg
- Zopfresh 10 mg

Final Verdict: Which Should You Choose?
- Choose Zopfresh if you’re a beginner or your insomnia is mild to moderate.
- Choose Zopinap if you’ve tried lower doses before and still can’t sleep, or if your insomnia is severe.
Bottom Line: Neither is “better” universally- the right choice depends on your condition, tolerance, and doctor’s guidance.

-
Is Zopinap stronger than Zopfresh?
A. Yes. Zopinap has a 20 mg option, making it stronger than Zopfresh’s maximum 10 mg.
-
Can I switch between them?
A. Yes, but only under medical guidance to avoid overdose or underdose.
-
How long does Zopiclone stay in your body?
A. Its half-life is about 5 hours, but effects can last 6–8 hours.
-
Which is safer?
A. Both are safe when used as prescribed. Zopfresh’s lower doses may be safer for new users.
-
Can I take them every night?
A. Only for 2–4 weeks. Long-term nightly use risks dependence.
-
Can I drink alcohol while taking them?
A. No. Alcohol combined with Zopiclone is dangerous and can depress breathing.
-
Where can I buy safely?
A. On MyMedicineMart.com, where trusted suppliers are verified and prices are compared for you.